Divanil ER 250 is an Extended Release formulation of Divalproex Sodium, an anticonvulsant medication used to help stabilize excessive and abnormal nerve activity in the brain. The extended-release form is designed for once-daily dosing, helping to maintain a steady level of the drug in the body throughout the day.

Therapeutic Uses

Divanil ER 250 is primarily used under medical supervision for the treatment of:

1. Epilepsy (Seizures/Fits): Used to treat various types of seizures, including complex partial seizures, and simple and complex absence seizures, either alone or in combination with other medications. It works by controlling the frequency and severity of seizures.

2. Bipolar Disorder (Manic Episodes): Used to manage the manic episodes associated with bipolar disorder, helping to stabilize mood and reduce agitation and extreme mood swings.

3. Migraine Prophylaxis: Used to prevent migraine headaches in adults (it is not for treating an already existing migraine attack).

Note: The uses of this medicine are based on its active ingredient Divalproex Sodium. Always consult your doctor for the exact indication for your treatment.

How Divanil ER 250 Works

The active ingredient, Divalproex Sodium, is converted into valproic acid in the body. It exerts its therapeutic effect through multiple mechanisms in the central nervous system, mainly by:

· Increasing GABA Levels: It increases the concentration of Gamma-Aminobutyric Acid (GABA), a major inhibitory neurotransmitter in the brain. By boosting GABA, it helps to \\\"calm down\\\" overactive nerve signals, which in turn helps control seizures and stabilize mood.

· Modulating Ion Channels: It can also suppress rapid, repetitive firing of nerve cells by affecting voltage-sensitive sodium and calcium channels.

The extended-release technology ensures a prolonged and consistent action, contributing to its effectiveness with convenient once-daily dosing.

Directions for Use

· Take Divanil ER 250 exactly as prescribed by your doctor.

· Swallow the tablet whole. Do not chew, crush, or break the tablet, as this will destroy the extended-release mechanism and could increase side effects.

· It can be taken with or without food. Taking it with food may help reduce stomach upset.

· Take it at the same time each day to maintain consistent drug levels.

· Do not stop taking this medicine suddenly, even if you feel well, as this can trigger seizures or worsen your condition. Any dose changes or discontinuation must be done only under the guidance of your doctor.

Safety and Warnings (Consult Your Doctor)

While generally safe when used as directed, Divalproex Sodium carries potential risks. It is essential to discuss your complete medical history with your doctor before starting this medication.